Check with your doctor right away if you have sudden and severe stomach pain, chills, constipation, nausea, vomiting, fever, or lightheadedness. This medicine may cause serious types of allergic reactions, including anaphylaxis and angioedema. Anaphylaxis and angioedema can be life-threatening and require immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, mouth, or throat while you are using this medicine.
Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine. Do not eat grapefruit or drink grapefruit juice while you are using this medicine. Grapefruit and grapefruit juice may cause the amount of medicine in the blood to be too high. Do not take other medicines unless they have been discussed with your doctor.
This includes prescription or nonprescription over-the-counter [OTC] medicines and herbal e. John's wort or vitamin supplements. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs. How does Prempro treat menopausal symptoms? Stacy Wiegman, PharmD. While taking Prempro, you will not have a monthly menstrual period. Nursing mothers: not recommended.
May be potentiated by CYP3A4 inhibitors eg, erythromycin, clarithromycin, ketoconazole, itraconazole, ritonavir, grapefruit juice. Concomitant thyroid replacement; may need to increase thyroid dose. Concomitant aminoglutethimide: may reduce bioavailability of medroxyprogesterone.
Abdominal pain, asthenia, back pain, headache, flatulence, nausea, depression, pruritus, breast pain, dysmenorrhea, leukorrhea; thromboembolism, neoplasms, anaphylaxis, angioedema permanently discontinue if occurs. Adult Dosage: 1 tab once daily. Children Dosage: Not applicable. Boxed Warning: Endometrial cancer. Breast cancer. Treatment of menopausal symptoms with hormone therapy.
Accessed March 25, Menopausal hormone therapy: Benefits and risks. American College of Obstetricians and Gynecologists. Practice Bulletin No. Reaffirmed North American Menopause Society.
Nonhormonal management of menopause-associated vasomotor symptoms: position statement of The North American Menopause Society.
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